Crystal engineering in the pharmaceutical industry

General data

Course ID:	0600-OG-EN-CEPI
Erasmus code / ISCED:	13.3 Kod klasyfikacyjny przedmiotu składa się z trzech do pięciu cyfr, przy czym trzy pierwsze oznaczają klasyfikację dziedziny wg. Listy kodów dziedzin obowiązującej w programie Socrates/Erasmus, czwarta (dotąd na ogół 0) – ewentualne uszczegółowienie informacji o dyscyplinie, piąta – stopień zaawansowania przedmiotu ustalony na podstawie roku studiów, dla którego przedmiot jest przeznaczony. / (0531) Chemistry The ISCED (International Standard Classification of Education) code has been designed by UNESCO.
Course title:	Crystal engineering in the pharmaceutical industry
Name in Polish:	Crystal engineering in the pharmaceutical industry
Organizational unit:	Faculty of Chemistry
Course groups:	(in Polish) Przedmioty ogólnouniwersyteckie - Wydział chemii General university courses
ECTS credit allocation (and other scores):	3.00 Basic information on ECTS credits allocation principles: the annual hourly workload of the student’s work required to achieve the expected learning outcomes for a given stage is 1500-1800h, corresponding to 60 ECTS; the student’s weekly hourly workload is 45 h; 1 ECTS point corresponds to 25-30 hours of student work needed to achieve the assumed learning outcomes; weekly student workload necessary to achieve the assumed learning outcomes allows to obtain 1.5 ECTS; work required to pass the course, which has been assigned 3 ECTS, constitutes 10% of the semester student load.
Language:	English
Prerequisites:	none
Total student workload:	Contact hours with teacher: - participation in lectures 30 hrs - consultation with lecturer 10 hrs Self-study hours: - reading literature - 10 hrs - preparation for examination - 25 hrs Altogether: 75 hrs (3 ECTS)
Learning outcomes - knowledge:	W1: has basic knowledge of issues faced in the pharmaceutical industry connected with the solid-state W2: knows about polymorphs and their impact on pharmaceutical development W3: is familiar with basic concepts of crystal engineering, e.g. intermolecular interactions W4: is acquainted with a range of crystalline materials and their methods of characterization W5: has basic knowledge on the significance of structural properties from a patent perspective
Learning outcomes - skills:	U1: is able to list issues in the pharmaceutical industry related to the solid-state U2: is capable of identifying different polymorphic forms U3: has basic skills in indicating different types of crystalline materials U4: can explain the importance of solid-state properties on the protection of Intellectual Property
Learning outcomes - social competencies:	K1: understands the significance of multi-disciplinary collaboration within the pharmaceutical industry K2: understands the need for basic research to support pharmaceutical development K3: recognizes the importance of the interplay between research and Intellectual Property
Teaching methods:	informative lecture
Expository teaching methods:	- informative (conventional) lecture
Short description:	The lecture series aims to familiarize students with everyday issues faced by the pharmaceutical industry related to solid matter.
Full description:	The lectures will cover such areas as: 1. Molecular/crystal structures and their visualisation 2. Intermolecular interactions 3. Crystal engineering 4. Polymorphism and problems connected with its appearance in the pharmaceutical industry 5. Methods to characterize polymorphs 6. Crystal lattice energies and crystal structures prediction methods 6. Multi-component crystals 7. Patent matters
Bibliography:	1) Crystal Engineering, a textbook, G.R. Desiraju, J.J. Vittal, A. Ramanan 2011, World Scientific Publishing 2) Polymorphism in Molecular Crystals, J. Bernstein, 2007, Oxford Science Publications 3) Polymorphism in Pharmaceutical Solids, H. G. Brittain, 2009, Taylor & Francis Inc.
Assessment methods and assessment criteria:	- Written exam 1-2 hours. Criteria: Fail (< 50%) Satisfactory (50-60%) – the student has basic understanding of the formation of different types of crystalline solids Satisfactory plus for the grade (61-65%) – the student has basic understanding of the formation of different types of crystalline solids and knowledge of various intermolecular interactions Good (66-75%) – the student has basic understanding of the formation of different types of crystalline solids and knowledge of various intermolecular interactions. He/she understands the concept of polymorphism and its significance within the pharmaceutical industry. Good plus (76-80%) – the student has basic understanding of the formation and characterization of different types of crystalline solids and knowledge of various intermolecular interactions. He/she understands the concept of polymorphism and its significance within the pharmaceutical industry. The student has knowledge on the importance of solid-state properties in relationship to Intellectual Property. Very good (> 80%) Has in-depth knowledge of all aspects of the subject matter.
Practical placement:	not applicable

Classes in period "Summer semester 2024/25" (future)

Time span:	2025-02-24 - 2025-09-30	Selected timetable range: weekly course term Navigate to timetable
Type of class:	Lecture, 30 hours, 100 places more information
Coordinators:	Liliana Dobrzańska
Group instructors:	Liliana Dobrzańska
Students list:	(inaccessible to you)
Examination:	Course - Examination Lecture - Examination

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