2.1. Patofizjologia

To realize the described subject it is necessary to know elements of anatomy, physiology and biochemistry.

przedmiot obowiązkowy

Study hours involving teacher participation:

- lectures - 15 hours,

- tutorials - 40 hours,

- seminars - 0 hours;

Study hours involving individual student work:

- reading literature – 10 hours,

- preparation for test – 20 hours,

- preparation for final test - 15 hours;

Total: 100 hours (4 ECTS)

Student:

W1: defines the clinical course of specific and non-specific inflammations, and describes the processes of tissue and organ regeneration - C K_W27

W2: knows the definition and pathophysiology of shock, with special regard to the various causes of shock and multiple organ failure - C K_W28

W3: knows concepts related to specific organ pathology, macroscopic and microscopic images and the clinical course of pathomorphological changes in individual organs - C K_W30

W4: enumerates internal and external, modifiable and non-modifiable pathogenic factors - C K_W32

W5: enumerates the clinical manifestations of the most common diseases of individual organs and systems, metabolic diseases, and water-electrolyte and acid-base imbalance - C K_W33

W6: knows basic directions of the development of medical treatment, particularly the possibilities of cell therapy, gene therapy and targeted therapy in selected diseases - C K_W41

Student:

U1: correlates images of tissue and organ damage with the clinical symptoms of disease, medical history and results of laboratory determinations - C K_U11

Student:

K1: is aware of own limitations and is able to pursue continuing education - K_K01

K2: is able to establish and maintain close and respectful relationships with patients - K_K03

K3: has the habit of and skills related to pursuing continuing education - K_K08

Observation/demonstration teaching methods

- display

- simulation (simulation games)

Expository teaching methods

- description

- discussion

- informative (conventional) lecture

- participatory lecture

- problem-based lecture

Exploratory teaching methods

- practical

- experimental

- classic problem-solving

- laboratory

- round table

- presentation of a paper

- case study

- pokaz
- symulacyjna (gier symulacyjnych)

- opis
- pogadanka
- wykład informacyjny (konwencjonalny)
- wykład konwersatoryjny
- wykład problemowy

- ćwiczeniowa
- doświadczeń
- klasyczna metoda problemowa
- laboratoryjna
- okrągłego stołu
- referatu
- studium przypadku

Pathophysiology describes etiology and origins of mechanisms for functional disorders within an organism in various pathological stages. It covers cellular pathophysiology, pathophysiology of organs and systems, issues in relation to changes in adaptation functions of organisms, disorders of organism’s regulatory functions, metabolic disorders and pathophysiology of cancer.

Pathophysiology course focuses on acquiring knowledge and skills in the field of etiology of disorders in adaptation and regulatory functions and metabolic disorders in humans. Students will gain knowledge of mechanisms responsible for causing the disorders in individual organs and systems, functional changes they lead to and the overall consequences to an organism. Students will also aquire skills used in laboratory diagnostics. Tutorials will equip students with knowledge essential to recognise and assess conditions and limitations caused by diseases.

Pathophysiology course focuses on acquiring knowledge and skills in the field of etiology of disorders in adaptation and regulatory functions and metabolic disorders in humans. Students will gain knowledge of mechanisms responsible for causing the disorders in individual organs and systems, functional changes they lead to and the overall consequences to an organism. Students will also aquire skills used in laboratory diagnostics. Tutorials will equip students with knowledge essential to recognise and assess conditions and limitations caused by diseases.

Lectures (45 minutes)

1. Pathophysiology. Etiology and pathogenesis of the disease.

2. Hemostatic mechanisms.

3. Fibrinolysis.

4. Kininogenesis.

5. Pathogenesis of thrombosis.

6. Pathogenesis of atherosclerosis.

7. Coronary heart disease.

8. Pathogenesis of myocardial infarction.

9. Pathogenesis of hypertension.

10. Heart failure.

11. Compensation mechanisms of the cardiovascular system.

12. Pathogenesis of shock.

13. Types of shock.

14. Pathogenesis of inflammation.

15. Etiopathogenesis of cancer.

Tutorials (135 minutes)

1. Pathophysiology of the respiratory system.

2. Pathological changes in ECG. Heart rhythm disorders.

3. Valvular heart disease.

4. Myocardial infarction. Heart failure.

5. Disorders of erythropoietic system.

6. Disorders of leucocytic system.

7. Pathophysiology of hemostasis. Thrombosis.

8. Pathogenesis of acute renal failure and chronic kidney disease. Signs and symptoms of renal failure.

9. Pathogenesis of hemorrhagic diathesis.

10. Acid-base disorders.

11. Pathology of the liver. Pathology of the digestive system.

12. Disorders of the pituitary and thyroid gland.

13. Disorders of the adrenal glands. Disorders of the reproductive system.

14. Disorders of the parathyroid glands. Osteoporosis.

15. Pathogenesis of diabetes mellitus.

Primary literature

1. McPhee SJ, Ganong WF: Pathophysiology of Disease: An Introduction to Clinical Medicine. International Edition. McGraw-Hill, 2006, 5th edition.

2. Copstead L, Banasik J: Pathophysiology. Elsevier, 2013, 5th edition.

Supplementary literature

1. Prawon D, Singer CRJ, Baglin T: Oxford handbook of Clinical Haematology. Oxford University, 2004.

2. Klatt EC, Kuman V: Robbins and Cotran Review of Pathology. W. B. Saunders Company, 2009, 3rd edition.

Assessment methods

Written tests - W1, W2, W3, W4, W5, W6, U1

Activity in tutorials - U1, K1, K2, K3

Final test - W1, W2, W3, W4, W5, W6, U1

Assessment criteria

fail - 0-55%

satisfactory - 56-67%

satisfactory plus - 68-75%

good - 76-83%

good plus - 84-91%

very good - 92-100%

Not applicable.